Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431911 | 0.93 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL19465186 | 0.85 | ITGAV (0.57) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL6222793 | 0.85 | ITGAV (0.49) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL6433481 | 0.84 | ITGAV (0.49) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL6225565 | 0.83 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL6222791 | 0.78 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL30336559 | 0.77 | ITGAV (0.55) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL7415000 | 0.77 | ITGAV (0.55) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL20481203 | 0.76 | ITGAV (0.57) | ITGAVITGB6ITGB3ITGA2BITGB5 | |
| SCHEMBL6421610 | 0.75 | ITGAV (0.63) | ITGAVITGB6ITGB3ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044001-B1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2005-07-06 | — | — | EP | disclosed |