⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131822 | 0.94 | — | — | |
| SCHEMBL4671938 | 0.92 | CYP19A1 (0.30) | — | |
| SCHEMBL4675178 | 0.92 | CYP19A1 (0.30) | — | |
| SCHEMBL133874 | 0.92 | CYP19A1 (0.30) | — | |
| SCHEMBL197020 | 0.88 | — | — | |
| SCHEMBL1448141 | 0.70 | — | — | |
| SCHEMBL16593474 | 0.69 | — | — | |
| SCHEMBL7487741 | 0.69 | — | — | |
| SCHEMBL8915038 | 0.69 | — | — | |
| SCHEMBL9052834 | 0.68 | CYP19A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151188-A1 | GREEN SYNTHESIS METHOD OF ANTIVIRAL DRUG INTERMEDIATE | 上海皓元医药股份有限公司 | 2023-08-17 | — | — | WO | claimed |
| CN-114671798-B | Green synthesis method of antiviral drug intermediate | 上海皓元医药股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114671798-A | Green synthesis method of antiviral drug intermediate | 上海皓元医药股份有限公司 | 2022-06-28 | — | — | CN | claimed |
| US-10011581-B2 | Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-pentanoic acid compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-07-03 | — | — | US | claimed |
| US-20180118705-A1 | PROCESS FOR PREPARING 4-AMINO-5-BIPHENYL-4-YL-2-HYDROXYMETHYL-2-METHYL-PENTANOIC ACID COMPOUND | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-05-03 | — | — | US | claimed |
| US-9676742-B2 | Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-pentanoic acid compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-06-13 | — | — | US | claimed |
| EP-2814819-B1 | PROCESS FOR PREPARING 4-AMINO-5-BIPHENYL-4-YL-2-HYDROXYMETHYL-2-METHYL-PENTANOIC ACID COMPOUNDS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2016-11-02 | — | — | EP | claimed |
| US-20150291546-A1 | PROCESS FOR PREPARING 4-AMINO-5-BIPHENYL-4-YL-2-HYDROXYMETHYL-2-METHYL-PENTANOIC ACID COMPOUND | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-10-15 | — | — | US | claimed |
| US-9096577-B2 | Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-pentanoic acid compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-08-04 | — | — | US | claimed |
| CN-102725285-B | (3-fluoro-2-hydroxy) propyl-functional aryl derivative or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition for diagnosing or treating brain degenerative diseases comprising same as active ingredient | FUTURECHEM CO LTD | 2015-05-20 | — | — | CN | claimed |
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| EP-0134986-B1 | BIOLOGICALLY ACTIVE HEPTAPEPTIDES, AGENTS THEREOF AND THEIR USE | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-12-27 | — | — | EP | claimed |
| US-4857520-A | Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | claimed |
| EP-0175323-A2 | Biologically active peptides, processes for preparing them and pharmaceutical compositions | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-03-26 | — | — | EP | claimed |
| US-4567162-A | ANIMAL GROWTH PROMOTERS | FARMITALIA CARLO ERBA (IT) | 1986-01-28 | — | — | US | claimed |
| EP-0134986-A2 | Biologically active heptapeptides, agents thereof and their use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1985-03-27 | — | — | EP | claimed |
| US-4491541-A | Peptides | FARMITALIA CARLO ERBA | 1985-01-01 | — | — | US | claimed |
| US-4474765-A | Biologically active peptides | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-10-02 | — | — | US | claimed |
| US-4205183-A | Facile method for isolating resolved amino acids | BECKMAN INSTRUMENTS, INC. (US) | 1980-05-27 | — | — | US | claimed |
| US-3948971-A | N-protected-α-amino acid compounds | MERCK & CO., INC. (US) | 1976-04-06 | — | — | US | claimed |