Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 4/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18606689 | 0.86 | CA1 (0.73) | CA1CA2CA9KMT2AHPGD | |
| SCHEMBL10327420 | 0.86 | CA1 (0.71) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL6223654 | 0.85 | CA1 (0.64) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL12163171 | 0.84 | KMT2A (0.73) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL14372406 | 0.84 | ALDH1A1 (0.66) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL14679073 | 0.83 | GAA (0.76) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL6227210 | 0.82 | CA1 (1.00) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL12131737 | 0.81 | F10 (0.61) | HPGDSMN1; SMN2 | |
| SCHEMBL679010 | 0.81 | HPGD (0.74) | KMT2AHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6223450 | 0.81 | CA1 (1.00) | CA1CA2CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775110-B1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | EP | claimed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | claimed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |