Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331208 | 0.84 | GPR17 (0.46) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL29951196 | 0.81 | ERN1 (0.48) | ABCG2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL5716781 | 0.79 | POLB (0.49) | ABCG2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL9186020 | 0.78 | GPR17 (0.64) | ALDH1A1KDM4EHPGDGPR17HSD17B10 | |
| SCHEMBL19330865 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL19331407 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL8054562 | 0.77 | ALDH1A1 (0.61) | ABCG2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL1144751 | 0.75 | GPR17 (0.64) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL19331452 | 0.74 | GPR17 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL29588320 | 0.74 | ABCG2 (0.60) | ABCG2MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068858-B1 | Use of 4,6-dimethoxyindole-2-carboxylic acid for stimulating or inducing hair growth and/or arresting hair loss | OREAL (FR) | 2005-04-13 | — | — | EP | claimed |
| EP-1068865-B1 | Use of 4,6-dimethoxy-indole 2-carboxylic acid or derivatives thereof for seborrhea treatment | OREAL (FR) | 2005-03-16 | — | — | EP | claimed |