Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128278 | 0.82 | NR3C1 (0.74) | NR3C1NR3C2PGRHTR2AHTR2C | |
| SCHEMBL3121769 | 0.81 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL3124783 | 0.80 | NR3C1 (1.00) | NR3C1NR3C2PGRHTR2AHTR2C | |
| SCHEMBL3124956 | 0.80 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL3124879 | 0.79 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL3124976 | 0.78 | NR3C1 (0.81) | NR3C1NR3C2PGR | |
| SCHEMBL3124837 | 0.78 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL3130558 | 0.77 | NR3C1 (0.75) | NR3C1NR3C2PGR | |
| SCHEMBL3124928 | 0.75 | NR3C1 (0.68) | NR3C1NR3C2PGR | |
| SCHEMBL3125833 | 0.75 | NR3C1 (0.80) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539141-A1 | -3 (SULFONAMIDOETHYL) -INDOLE DERIVATIES FOR USE AS GLUCOCORTICOID MIMETICS IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND PROLIFERATIVE DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004019935-A1 | -3 (SULFONAMIDOETHYL) -INDOLE DERIVATIES FOR USE AS GLUCOCORTICOID MIMETICS IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND PROLIFERATIVE DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | claimed |