Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409004 | 0.78 | MAPT (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2910992 | 0.77 | CYP17A1 (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11935888 | 0.77 | MAPT (0.49) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16737101 | 0.77 | ABCG2 (0.43) | NPC1TUBB1MEN1KMT2AALDH1A1 | |
| SCHEMBL1157334 | 0.76 | PDE4A (0.50) | MRGPRX1NPC1MAPTALDH1A1HDAC1 | |
| SCHEMBL2902811 | 0.76 | MAPT (0.64) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1157896 | 0.74 | MRGPRX1 (0.47) | MRGPRX1NPC1DHFRHDAC1HDAC2 | |
| SCHEMBL1239663 | 0.74 | BCL6 (0.45) | TUBB1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1157239 | 0.74 | MRGPRX1 (0.44) | MRGPRX1NPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL2905635 | 0.73 | MAPT (0.71) | MRGPRX1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515968-A2 | QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Almirall Prodesfarma AG (CH) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000840-A2 | QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | ALMIRALL PRODESFARMA AG (CH) | 2003-12-31 | — | — | WO | disclosed |