SCHEMBL6227690

SCHEMBL6227690

Cc1ccc2c(c1)Cc1c-2ccc(C)c1[Zr](=[SiH2])(C1=CC=CC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
METAP1 P53582 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5084091 0.99 MAPT (0.32) MAPTKDM4EALDH1A1POLBGAA
SCHEMBL6226859 0.93 METAP1 (0.32) MAPTMETAP1MEN1KMT2A
SCHEMBL6232662 0.93 MAPT (0.32) MAPTKDM4EALDH1A1POLBGAA
Hydrochloric Acid SCHEMBL5083371 0.92 METAP1 (0.32) MAPTMETAP1MEN1KMT2A
Hydrochloric Acid SCHEMBL5081235 0.92 KDM4E (0.32) MAPTKDM4EALDH1A1POLBGAA
Hydrochloric Acid SCHEMBL7086362 0.89 NPC1 (0.32) RAB9A
SCHEMBL6003787 0.83 MEN1 (0.33) MAPTMETAP1MEN1KMT2A
Hydrochloric Acid SCHEMBL5081166 0.82 MEN1 (0.33) MAPTMETAP1MEN1KMT2A
Hydrochloric Acid SCHEMBL7082745 0.82 TDP2 (0.33)
SCHEMBL7251519 0.81 NPC1 (0.32) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511305-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-10-17 EP disclosed
EP-2465878-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-2465879-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-1548018-A1 CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME Mitsui Chemicals, Inc. (JP) 2005-06-29 EP disclosed