SCHEMBL6227751

SCHEMBL6227751

CON=C(C(N)=O)c1ccccc1CBr

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.44
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.34
CYP2C19 P33261 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
CTSD P07339 1/20 0.34
GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156649 1.00 HIF1A (0.44) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL27390096 0.88 HIF1A (0.43) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL27541830 0.88 HIF1A (0.43) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL7913279 0.86 HIF1A (0.45) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL5630085 0.86 HIF1A (0.46) HIF1AALDH1A1LMNAKMT2AMAPT
SCHEMBL7457790 0.86 HIF1A (0.46) HIF1AALDH1A1LMNAKMT2AMAPT
SCHEMBL3459416 0.86 HIF1A (0.46) HIF1AALDH1A1LMNAKMT2AMAPT
SCHEMBL8078567 0.86 HIF1A (0.45) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL10433828 0.86 HIF1A (0.45) HIF1AALDH1A1LMNATDP1L3MBTL1
SCHEMBL30714836 0.86 HIF1A (0.46) HIF1AALDH1A1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1026151-B1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides DOW AGROSCIENCES LLC (US) 2005-03-16 EP disclosed
EP-0936213-B1 Unsaturated oxime ethers and their use as fungicides and insecticides DOW AGROSCIENCES LLC (US) 2003-03-26 EP disclosed
EP-1050528-B1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds DOW AGROSCIENCES LLC (US) 2003-01-22 EP disclosed
WO-2002012172-A1 UNSATURATED OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2002-02-14 WO disclosed
EP-0711759-B1 Pyridazinones and their use as fungicides DOW AGROSCIENCES LLC (US) 2002-01-09 EP disclosed
US-6335367-B1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds DOW AGROSCIENCES LLC 2002-01-01 US disclosed
US-6303818-B1 Unsaturated oxime ethers and their use as fungicides DOW AGROSCIENCES LLC 2001-10-16 US disclosed
EP-0811608-B1 Benzyloxy substituted aromatics containing an acrylyl moiety and their use as fungicides and insecticides ROHM & HAAS (US) 2001-03-21 EP disclosed
US-6177462-B1 Unsaturated oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY 2001-01-23 US disclosed
EP-1050528-A1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds ROHM AND HAAS COMPANY (US) 2000-11-08 EP disclosed
EP-1026151-A1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 2000-08-09 EP disclosed
EP-1024135-A1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 2000-08-02 EP disclosed
US-6063956-A APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED ROHM AND HAAS COMPANY (US) 2000-05-16 US disclosed
EP-0936213-A1 Unsaturated oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1999-08-18 EP disclosed
EP-0889024-A1 Benzyloxy substituted aromatics and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1999-01-07 EP disclosed
EP-0811614-A1 Benzyloxy substituted aromatics and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1997-12-10 EP disclosed
EP-0811608-A1 Benzyloxy substituted aromatics containing an acrylyl moiety and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1997-12-10 EP disclosed
US-5635494-A CONTROLLING PHYTOPATHOGENIC FUNGI, INSECTS ROHM AND HAAS COMPANY (US) 1997-06-03 US disclosed
EP-0738716-A2 Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1996-10-23 EP disclosed
EP-0711759-A1 Pyridazinones and their use as fungicides ROHM AND HAAS COMPANY (US) 1996-05-15 EP disclosed