Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21460045 | 1.00 | TSHR (0.43) | TSHRACHEGABRA1GABRB2CASR | |
| Bromide SCHEMBL28723982 | 0.98 | TSHR (0.41) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL164361 | 0.97 | TSHR (0.45) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL29581427 | 0.97 | TSHR (0.45) | TSHRACHEGABRA1GABRB2CASR | |
| Hydrochloric Acid SCHEMBL23886258 | 0.95 | TDP1 (0.44) | TSHRACHEGABRA1GABRB2CASR | |
| Fluoride SCHEMBL1502827 | 0.95 | TSHR (0.43) | TSHRACHEGABRA1GABRB2CASR | |
| Ammonia Solution, Strong SCHEMBL5145133 | 0.95 | TSHR (0.43) | TSHRACHEGABRA1GABRB2CASR | |
| Water SCHEMBL93584 | 0.95 | TSHR (0.43) | TSHRACHEGABRA1GABRB2CASR | |
| Hydrochloric Acid SCHEMBL136350 | 0.95 | TDP1 (0.44) | TSHRACHEGABRA1GABRB2CASR | |
| Iodide SCHEMBL1502892 | 0.95 | TSHR (0.43) | TSHRACHEGABRA1GABRB2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116145156-B | Indoline compound preparation method based on organic electronic synthesis | 六盘水师范学院 | 2026-05-15 | — | — | CN | claimed |
| CN-119874616-B | Organic intermediate and preparation method and application thereof | 四川美域高生物医药科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119874616-A | Novel organic intermediate and preparation method and application thereof | 四川美域高生物医药科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-115957618-B | Hydrogen sulfide leakage emergency spray treating agent and use method thereof | 中国石油化工股份有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-115746249-B | Castor oil-based water-based UV (ultraviolet) curing polyurethane acrylate as well as preparation method and application thereof | 华南农业大学 | 2024-06-25 | — | — | CN | claimed |
| CN-112499642-B | Preparation method of multichannel SSZ-13 molecular sieve membrane | 南京工业大学 | 2023-11-21 | — | — | CN | claimed |
| CN-113045416-B | Preparation method of (R) -3-hydroxybutyryl- (R) -3-hydroxybutyl ester | 南京纽邦生物科技有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-116177558-A | Zirconium-silicon CHA molecular sieve and preparation method and application thereof | 国家能源集团科学技术研究院有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115746249-A | Castor oil-based waterborne UV-cured polyurethane acrylate as well as preparation method and application thereof | 华南农业大学 | 2023-03-07 | — | — | CN | claimed |
| CN-112645344-B | Method for preparing SSZ-13 molecular sieve membrane by steam-assisted conversion | 南京工业大学 | 2023-01-24 | — | — | CN | claimed |
| CN-108579449-B | Method for rapidly synthesizing high-silicon SSZ-13 molecular sieve membrane | 南京工业大学 | 2019-12-17 | — | — | CN | claimed |
| EP-1006374-B1 | Process for producing a resin having a large refractive index | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-01-07 | — | — | EP | claimed |
| JP-3280030-B2 | — | — | 2002-04-30 | — | — | JP | claimed |
| EP-0749450-B1 | COATING COMPOSITION AND PROCESS FOR FORMING CURED FILM | NIPPON PAINT CO LTD (JP) | 2000-07-05 | — | — | EP | claimed |
| US-5766767-A | Coating composition process for forming cured film and coated article | NIPPON PAINT CO., LTD. (JP) | 1998-06-16 | — | — | US | claimed |
| EP-0749450-A1 | COATING COMPOSITION, PROCESS FOR FORMING CURED FILM AND COATED ARTICLE | NIPPON PAINT CO., LTD. (JP) | 1996-12-27 | — | — | EP | claimed |
| WO-1995023820-A1 | COATING COMPOSITION, PROCESS FOR FORMING CURED FILM AND COATED ARTICLE | NIPPON PAINT CO., LTD. (JP) | 1995-09-08 | — | — | WO | claimed |
| US-5380804-A | 1,3,5-tris-(2-carboxyethyl) isocyanurate crosslinking agent for polyepoxide coatings | CYTEC TECHNOLOGY CORP. (US) | 1995-01-10 | — | — | US | claimed |
| US-4056547-A | FROM AN ALKALI METAL OR AMMONIUM CYANATE AND A BENZYL CHLORIDE, CATALYST | KAO SOAP CO., LTD. (JA) | 1977-11-01 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |