⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113047 | 0.86 | ALDH1A1 (0.54) | — | |
| SCHEMBL3124337 | 0.84 | MAPT (0.54) | — | |
| SCHEMBL18874520 | 0.83 | — | — | |
| SCHEMBL3110133 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL3118989 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL3112105 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL3112734 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL3112942 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL10311849 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL7301068 | 0.79 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346377-B1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PRYSMIAN CAVI SISTEMI ENERGIA (IT) | 2007-06-13 | — | — | EP | claimed |
| US-6903263-B2 | Electrical cable, particularly for high voltage direct current transmission or distribution, and insulating composition | PIRELLI, S.P.A. (IT) | 2005-06-07 | — | — | US | claimed |
| US-20040091707-A1 | Electrical cable, particularly for high voltage direct current transmission or distribution, and insulating composition | PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) | 2004-05-13 | — | — | US | claimed |
| EP-1346377-A1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PIRELLI S.p.A. (IT) | 2003-09-24 | — | — | EP | claimed |
| WO-2002052582-A1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PIRELLI S.P.A. (IT) | 2002-07-04 | — | — | WO | claimed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| CN-113620936-B | Pyrrolidine compound and application thereof | 上海药明康德新药开发有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20220168385-A1 | USE OF CYCLOSPORINE ANALOGUES AS ANTITHROMBOTIC AGENTS | ACHILLE LIFE SCIENCES LIMITED (GB) | 2022-06-02 | — | — | US | disclosed |
| WO-2022115651-A1 | USE OF CYCLOSPORINE ANALOGUES AS ANTITHROMBOTIC AGENTS | HEPION PHARMACEUTICALS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| CN-108699013-B | Spiroquinone derivative, method for preparing the same, and pharmaceutical composition for preventing or treating neurological disorders containing the same as an active ingredient | 嘉泉大学校校产学协力团 | 2022-05-06 | — | — | CN | disclosed |
| CN-113620936-A | Pyrrolidine compound and application thereof | 上海药明康德新药开发有限公司 | 2021-11-09 | — | — | CN | disclosed |
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-9714271-B2 | Cyclosporine analogue molecules modified at amino acid 1 and 3 | CONTRAVIR PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| WO-2012021446-A2 | PROCESS FOR PREPARING ALISKIREN AND ITS INTERMEDIATES | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |
| WO-2009135299-A1 | 3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-11-12 | — | — | WO | disclosed |
| EP-1346377-B1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PRYSMIAN CAVI SISTEMI ENERGIA (IT) | 2007-06-13 | — | — | EP | disclosed |
| US-6903263-B2 | Electrical cable, particularly for high voltage direct current transmission or distribution, and insulating composition | PIRELLI, S.P.A. (IT) | 2005-06-07 | — | — | US | disclosed |
| US-20040091707-A1 | Electrical cable, particularly for high voltage direct current transmission or distribution, and insulating composition | PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) | 2004-05-13 | — | — | US | disclosed |