Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828572 | 0.92 | WEE1 (0.72) | WEE1CHEK1 | |
| SCHEMBL6227971 | 0.87 | WEE1 (0.73) | WEE1CHEK1 | |
| SCHEMBL5829004 | 0.85 | WEE1 (0.78) | WEE1CHEK1 | |
| SCHEMBL5828676 | 0.84 | WEE1 (0.84) | WEE1CHEK1 | |
| SCHEMBL5828031 | 0.84 | WEE1 (1.00) | WEE1CHEK1 | |
| SCHEMBL5829088 | 0.83 | WEE1 (0.78) | WEE1CHEK1 | |
| SCHEMBL5829115 | 0.83 | WEE1 (0.71) | WEE1CHEK1 | |
| SCHEMBL5829286 | 0.83 | WEE1 (1.00) | WEE1CHEK1 | |
| SCHEMBL5829042 | 0.80 | WEE1 (1.00) | WEE1CHEK1 | |
| SCHEMBL5828702 | 0.79 | WEE1 (1.00) | WEE1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501831-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091255-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-06 | — | — | WO | disclosed |