SCHEMBL6228397

SCHEMBL6228397

CCCCC(O)COc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.37
ADRB1 P08588 2/20 0.37
SMN1; SMN2 Q16637 5/20 0.36
TP53 P04637 4/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 2/20 0.36
MAPK1 P28482 2/20 0.36
PLA2G4B P0C869 1/20 0.36
POLB P06746 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
S1PR1 P21453 1/20 0.35
TSHR P16473 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30847778 0.96 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL30310082 0.96 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL14480155 0.96 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL14480246 0.96 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL12755357 0.94 SMN1; SMN2 (0.40) ADRB2ADRB1SMN1; SMN2TP53MAPK1
SCHEMBL12755330 0.91 ADRB2 (0.43) ADRB2ADRB1NPC1RAB9AMAPK1
SCHEMBL2511599 0.90 NPC1 (0.35) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL7128120 0.90 ADRB2 (0.42) ADRB2ADRB1SMN1; SMN2NPC1RAB9A
SCHEMBL39738 0.89 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1
SCHEMBL15721408 0.89 PLA2G4B (0.39) ADRB2ADRB1SMN1; SMN2TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492069-B2 Lithographic printing plate precursor and plate making method of lithographic printing plate FUJIFILM CORPORATION (JP) 2013-07-23 US disclosed
US-20110076616-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
EP-1089986-B1 POLY-TRISARYL-1,3,5-TRIAZINE CARBAMATE ULTRAVIOLET LIGHT ABSORBERS CIBA SC HOLDING AG (CH) 2005-03-30 EP disclosed
US-6306939-B1 PHOTOSTABILITY, PHOTOGRAPHIC MATERIALS CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-23 US disclosed
EP-1089986-A1 POLY-TRISARYL-1,3,5-TRIAZINE CARBAMATE ULTRAVIOLET LIGHT ABSORBERS Ciba SC Holding AG (CH) 2001-04-11 EP disclosed
WO-1999067227-A1 POLY-TRISARYL-1,3,5-TRIAZINE CARBAMATE ULTRAVIOLET LIGHT ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO disclosed