Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL4959926 | 0.97 | TSHR (0.62) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL7510054 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL8370309 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL8467361 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL3209520 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL2474192 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL20565539 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL21569402 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL21569383 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL11054858 | 0.93 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1665686-A | Method of conditioning a lithographic printing plate | FLINT INK CORP (US) | 2005-09-07 | — | — | CN | claimed |
| EP-1515856-A1 | METHOD OF CONDITIONING A LITHOGRAPHIC PRINTING PLATE | Flint Ink Corporation (US) | 2005-03-23 | — | — | EP | claimed |
| US-6854391-B2 | Lithographic printing method and materials | FLINT INK CORPORATION (US) | 2005-02-15 | — | — | US | claimed |
| WO-2003103980-A1 | METHOD OF CONDITIONING A LITHOGRAPHIC PRINTING PLATE | FLINT INK CORPORATION (US) | 2003-12-18 | — | — | WO | claimed |
| US-20030226462-A1 | Lithographic printing method and materials | FLINT INK CORPORATION | 2003-12-11 | — | — | US | claimed |
| US-9464253-B2 | Coal additive for improved furnace operation | THE LUBRIZOL CORPORATION (US) | 2016-10-11 | — | — | US | disclosed |
| CN-103361143-A | Coal additive for improved furnace operation | LUBRIZOL CORP | 2013-10-23 | — | — | CN | disclosed |
| US-20130260322-A1 | Coal Additive For Improved Furnace Operation | THE LUBRIZOL CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| CN-1665686-A | Method of conditioning a lithographic printing plate | FLINT INK CORP (US) | 2005-09-07 | — | — | CN | disclosed |
| EP-1515856-A1 | METHOD OF CONDITIONING A LITHOGRAPHIC PRINTING PLATE | Flint Ink Corporation (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6854391-B2 | Lithographic printing method and materials | FLINT INK CORPORATION (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2003103980-A1 | METHOD OF CONDITIONING A LITHOGRAPHIC PRINTING PLATE | FLINT INK CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030226462-A1 | Lithographic printing method and materials | FLINT INK CORPORATION | 2003-12-11 | — | — | US | disclosed |