⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230455 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6231152 | 0.70 | CYP2A6 (0.33) | — | |
| SCHEMBL325642 | 0.66 | — | — | |
| SCHEMBL8476471 | 0.64 | — | — | |
| SCHEMBL3703536 | 0.62 | — | — | |
| SCHEMBL1273687 | 0.62 | — | — | |
| SCHEMBL15600059 | 0.62 | — | — | |
| SCHEMBL13025284 | 0.51 | — | — | |
| SCHEMBL5150910 | 0.51 | — | — | |
| SCHEMBL4584646 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202979-B1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-04-27 | — | — | EP | claimed |
| US-20030191321-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | COPPOLA KEVIN (US) | 2003-10-09 | — | — | US | claimed |
| US-20030055229-A1 | Process for the preparation of thiazole derivatives | COPPOLA KEVIN (US) | 2003-03-20 | — | — | US | claimed |
| CN-1368966-A | Process for preparing thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2002-09-11 | — | — | CN | claimed |
| EP-1202979-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2002-05-08 | — | — | EP | claimed |
| US-6265553-B1 | INTERMEDIATES FOR INSECTICIDES | SYNGENTA CROP PROTECTION, INC. | 2001-07-24 | — | — | US | claimed |
| WO-2001010852-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-02-15 | — | — | WO | claimed |