SCHEMBL6230477

SCHEMBL6230477

CCC#CCOc1cc(N)c(Cl)cc1C(=O)NC1CC2C[C@@H](OC)C(C1)N2C

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 6/20 0.55
DRD2 P14416 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238270 1.00 HTR4 (0.55) HTR4DRD2
SCHEMBL6232979 1.00 HTR4 (0.55) HTR4DRD2
Hydrochloric Acid SCHEMBL6233395 0.99 HTR4 (0.54) HTR4DRD2
Hydrochloric Acid SCHEMBL6234071 0.99 HTR4 (0.54) HTR4DRD2
SCHEMBL6232424 0.90 HTR4 (0.55) HTR4DRD2
Hydrochloric Acid SCHEMBL6233042 0.86 HTR4 (0.69) HTR4DRD2
SCHEMBL6235633 0.85 HTR4 (0.60) HTR4DRD2
SCHEMBL6232982 0.85 HTR4 (0.65) HTR4DRD2
SCHEMBL6232466 0.85 HTR4 (0.60) HTR4DRD2
Hydrochloric Acid SCHEMBL6232972 0.84 HTR4 (0.59) HTR4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005007600-A2 NOVEL METHODS USING AMINOBENZOIC ACID COMPOUNDS EISAI CO., LTD. (JP) 2005-01-27 WO disclosed