Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.84 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6232922 | 0.98 | TERT (0.82) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL34460906 | 0.98 | TERT (0.87) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL6234260 | 0.98 | TERT (0.87) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL26378291 | 0.92 | TERT (1.00) | TERTKDM4EALDH1A1RECQLKMT2A | |
| Iodide SCHEMBL6233141 | 0.90 | TERT (0.97) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL34460911 | 0.90 | TERT (0.73) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6234517 | 0.89 | TERT (0.94) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL21367403 | 0.89 | TERT (1.00) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6231774 | 0.87 | TERT (0.64) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6234377 | 0.87 | TERT (0.64) | TERTSTAT3HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027879-B1 | Use of cationic condensed polycyclic compounds for dyeing of keratinic substances, dyeing compositions and process | OREAL (FR) | 2005-04-20 | — | — | EP | claimed |
| US-6391062-B1 | APPLYING A DIRECT DYE TO HAIR WITH BENZ(DE)ISOQUINOLINE ACID SALT COMPOUND | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | claimed |
| US-6391062-B1 | APPLYING A DIRECT DYE TO HAIR WITH BENZ(DE)ISOQUINOLINE ACID SALT COMPOUND | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | disclosed |