SCHEMBL6230992

SCHEMBL6230992

CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)[O-])cc1

nearest known ligand 0.46

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.46
LMNA P02545 2/20 0.46
CYP2D6 P10635 2/20 0.46
MAPK1 P28482 1/20 0.46
THPO P40225 1/20 0.46
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
CYP1A2 P05177 2/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RECQL P46063 1/20 0.41
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 4/20 0.40
MCHR1 Q99705 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9777641 0.93 CYP3A4 (0.41) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL11598787 0.91 PSIP1 (0.45) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL9634534 0.88 HIF1A (0.52) CYP3A4LMNACYP2D6MAPK1THPO
Butyltriphenylphosphonium SCHEMBL6928248 0.84 CNR2 (0.45) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL11051887 0.84 TDP1 (0.48) CYP3A4LMNACYP1A2L3MBTL1NPSR1
SCHEMBL4921374 0.84 CYP3A4 (0.46) CYP3A4LMNACYP2D6MAPK1THPO
Tetraphenylphosphonium SCHEMBL28641132 0.82 CA12 (0.46) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL9675753 0.82 NR1I2 (0.48) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL9634519 0.82 NR1I2 (0.48) CYP3A4LMNACYP2D6MAPK1THPO
SCHEMBL26120575 0.82 HIF1A (0.44) LMNACYP2D6CA12CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037114-A A THERMOSENSITIVE ELEMENT COMPRISING AN ORGANIC SILVER SALT AND A REDUCING AGENT EXHIBITING A NEUTRAL IMAGE TONE EXHIBIT AN INCREASE IN MAXIMUM IMAGE DENSITY AND IMAGE GRADATION UPON INCORPORATING A NON-HALIDE POLYARYLONIUM COMPOUND AGFA-GEVAERT (BE) 2000-03-14 US claimed
US-4496643-A PHOSPHONIUM, ARSONIUM, OR STIBONIUM COMPOUND IN BINDER AS TONER AND FLUOROCARBON CARRIER COATED PARTICLES EASTMAN KODAK COMPANY (US) 1985-01-29 US claimed
EP-0848286-B1 Thermographic recording material with improved image tone and/or stability upon thermal development AGFA GEVAERT (BE) 2005-04-06 EP disclosed
EP-0921434-B1 Thermographic recording material with improved image density and/or image gradation upon thermal development AGFA GEVAERT (BE) 2003-07-09 EP disclosed
US-6579671-B2 Comprises silver behenate, silver palmitate, and silver stearate; for thermographic or photothermographic development; x-rays AGFA-GEVAERT (BE) 2003-06-17 US disclosed
US-20020150849-A1 Recording materials with improved shelf-life, image tone and /or stability upon thermal development AGFA-GEVAERT (BE) 2002-10-17 US disclosed
US-6159667-A Thermographic recording material with improved image tone and/or stability upon thermal development AGFA-GEVAERT (BE) 2000-12-12 US disclosed
US-6096486-A SUPPORT, THERMOSENSITIVE ELEMENT CONTAINING SILVER BEHENATE, ORGANIC REDUCING AGENT, AND A BINDER, WHERE THE SILVER BEHENATE IS NOT ASSOCIATED WITH MERCURY OR LEAD IONS, HAS SPECIFIED X-RAY CHARACTERISTICS, AND INCREASED CRYSTALLINITY AGFA-GEVAERT (BE) 2000-08-01 US disclosed
US-6037114-A A THERMOSENSITIVE ELEMENT COMPRISING AN ORGANIC SILVER SALT AND A REDUCING AGENT EXHIBITING A NEUTRAL IMAGE TONE EXHIBIT AN INCREASE IN MAXIMUM IMAGE DENSITY AND IMAGE GRADATION UPON INCORPORATING A NON-HALIDE POLYARYLONIUM COMPOUND AGFA-GEVAERT (BE) 2000-03-14 US disclosed
EP-0921434-A1 Thermographic recording material with improved image density and/or image gradation upon thermal development AGFA-GEVAERT N.V. (BE) 1999-06-09 EP disclosed
EP-0848286-A1 Thermographic recording material with improved image tone and/or stability upon thermal development AGFA-GEVAERT N.V. (BE) 1998-06-17 EP disclosed
EP-0315082-B1 PROCESS FOR INCREASING THE ELECTROSTATIC CHARGEABILITY OF POWDER PAINTS OR POWDERS AND THEIR USE IN THE SURFACE COATING OF SOLID ITEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP disclosed
EP-0315082-A2 Process for increasing the electrostatic chargeability of powder paints or powders and their use in the surface coating of solid items HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP disclosed
EP-0161128-A1 Two-component dry electrostatic developer composition EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-11-13 EP disclosed