Phenylmethanesulfonic Acid

Phenylmethanesulfonic Acid

SCHEMBL6230993

CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=S(=O)([O-])Cc1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
CA9 Q16790 2/20 0.41
FAAH O00519 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
CA5A P35218 1/20 0.41
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
HIF1A Q16665 1/20 0.38
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylmethanesulfonic Acid SCHEMBL4921377 0.84 SNCA (0.47) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL4452744 0.84 CA2 (0.45) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL26120575 0.83 HIF1A (0.44) CA2CA9HIF1AKMT2AALDH1A1
Sulfuric Acid SCHEMBL11473943 0.82 HIF1A (0.43) CA2CA9HIF1AKMT2AALDH1A1
Phenylmethanesulfonic Acid SCHEMBL4463640 0.81 CA2 (0.50) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL135008 0.81 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL6232593 0.80 HIF1A (0.40) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL18419593 0.79 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL1565755 0.79 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL9812588 0.79 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037114-A A THERMOSENSITIVE ELEMENT COMPRISING AN ORGANIC SILVER SALT AND A REDUCING AGENT EXHIBITING A NEUTRAL IMAGE TONE EXHIBIT AN INCREASE IN MAXIMUM IMAGE DENSITY AND IMAGE GRADATION UPON INCORPORATING A NON-HALIDE POLYARYLONIUM COMPOUND AGFA-GEVAERT (BE) 2000-03-14 US claimed
EP-0848286-B1 Thermographic recording material with improved image tone and/or stability upon thermal development AGFA GEVAERT (BE) 2005-04-06 EP disclosed
EP-0921434-B1 Thermographic recording material with improved image density and/or image gradation upon thermal development AGFA GEVAERT (BE) 2003-07-09 EP disclosed
US-6579671-B2 Comprises silver behenate, silver palmitate, and silver stearate; for thermographic or photothermographic development; x-rays AGFA-GEVAERT (BE) 2003-06-17 US disclosed
US-20020150849-A1 Recording materials with improved shelf-life, image tone and /or stability upon thermal development AGFA-GEVAERT (BE) 2002-10-17 US disclosed
US-6159667-A Thermographic recording material with improved image tone and/or stability upon thermal development AGFA-GEVAERT (BE) 2000-12-12 US disclosed
US-6096486-A SUPPORT, THERMOSENSITIVE ELEMENT CONTAINING SILVER BEHENATE, ORGANIC REDUCING AGENT, AND A BINDER, WHERE THE SILVER BEHENATE IS NOT ASSOCIATED WITH MERCURY OR LEAD IONS, HAS SPECIFIED X-RAY CHARACTERISTICS, AND INCREASED CRYSTALLINITY AGFA-GEVAERT (BE) 2000-08-01 US disclosed
US-6037114-A A THERMOSENSITIVE ELEMENT COMPRISING AN ORGANIC SILVER SALT AND A REDUCING AGENT EXHIBITING A NEUTRAL IMAGE TONE EXHIBIT AN INCREASE IN MAXIMUM IMAGE DENSITY AND IMAGE GRADATION UPON INCORPORATING A NON-HALIDE POLYARYLONIUM COMPOUND AGFA-GEVAERT (BE) 2000-03-14 US disclosed
EP-0921434-A1 Thermographic recording material with improved image density and/or image gradation upon thermal development AGFA-GEVAERT N.V. (BE) 1999-06-09 EP disclosed
EP-0848286-A1 Thermographic recording material with improved image tone and/or stability upon thermal development AGFA-GEVAERT N.V. (BE) 1998-06-17 EP disclosed