Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540586 | 0.87 | MEN1 (0.54) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6539604 | 0.85 | MEN1 (0.53) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6540380 | 0.84 | MEN1 (0.52) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6206366 | 0.83 | MEN1 (0.56) | MEN1KMT2APABPC1ACACBACACA | |
| Hydrochloric Acid SCHEMBL6207662 | 0.82 | MEN1 (0.55) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6208425 | 0.79 | MEN1 (0.56) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6539764 | 0.77 | MEN1 (0.50) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6209712 | 0.75 | MEN1 (0.56) | MEN1KMT2APABPC1ACACBACACA | |
| SCHEMBL6199617 | 0.75 | MAPT (0.53) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6206679 | 0.75 | MEN1 (0.52) | MEN1KMT2APABPC1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | disclosed |