Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950591 | 0.82 | MEN1 (0.63) | MEN1PABPC1KMT2AACACBACACA | |
| SCHEMBL6208078 | 0.79 | MEN1 (0.60) | MEN1PABPC1KMT2AFFAR1BCHE | |
| SCHEMBL6206366 | 0.78 | MEN1 (0.56) | MEN1PABPC1KMT2AACACBACACA | |
| Hydrochloric Acid SCHEMBL6207662 | 0.78 | MEN1 (0.55) | MEN1PABPC1KMT2AACACBACACA | |
| SCHEMBL5183041 | 0.76 | MEN1 (0.56) | MEN1PABPC1KMT2AFFAR1LMNA | |
| SCHEMBL6208425 | 0.76 | MEN1 (0.56) | MEN1PABPC1KMT2AACACBACACA | |
| SCHEMBL7285420 | 0.76 | KMT2A (0.48) | MEN1PABPC1KMT2AACACBACACA | |
| SCHEMBL6231187 | 0.75 | MEN1 (0.55) | MEN1PABPC1KMT2AACACBACACA | |
| SCHEMBL10022963 | 0.75 | GSTP1 (0.58) | ACACBALOX5FFAR1BCHEMAOB | |
| SCHEMBL15340866 | 0.75 | FFAR1 (0.58) | ACACBACACAFFAR1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | disclosed |