N-Butylcinnamamide

N-Butylcinnamamide

SCHEMBL6231267

CCCCNC(=O)/C=C/c1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.88
KMT2A Q03164 1/20 0.81
HDAC3 O15379 3/20 0.73
HDAC1 Q13547 2/20 0.65
HDAC2 Q92769 2/20 0.65
HDAC4 P56524 1/20 0.65
HDAC7 Q8WUI4 1/20 0.65
HDAC10 Q969S8 1/20 0.65
HDAC11 Q96DB2 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
HDAC9 Q9UKV0 1/20 0.65
HDAC5 Q9UQL6 1/20 0.65
MMP1 P03956 2/20 0.65
MMP2 P08253 2/20 0.65
MMP9 P14780 2/20 0.65
POLB P06746 1/20 0.65
RECQL P46063 1/20 0.65
LMNA P02545 2/20 0.62
RAB9A P51151 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Butylcinnamamide SCHEMBL3688039 1.00 EGFR (0.88) EGFRKMT2AHDAC3HDAC1HDAC2
N-Pentylcinnamamide SCHEMBL7913716 0.95 EGFR (0.97) EGFRKMT2AHDAC3HDAC1HDAC2
N-Pentylcinnamamide SCHEMBL7913718 0.95 EGFR (0.97) EGFRKMT2AHDAC3HDAC1HDAC2
N-Hexadecylcinnamamide SCHEMBL2727701 0.94 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Dodecylcinnamamide SCHEMBL28975087 0.94 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
SCHEMBL28975079 0.94 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Dodecylcinnamamide SCHEMBL16596238 0.94 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Octylcinnamamide SCHEMBL10706126 0.94 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Propylcinnamamide SCHEMBL12224106 0.90 EGFR (0.77) EGFRKMT2AHDAC3HDAC1HDAC2
N-Propylcinnamamide SCHEMBL29040560 0.90 EGFR (0.77) EGFRKMT2AHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029457-B2 Silica-supported oligomeric hybrid materials THE UNIVERSITY OF KANSAS (US) 2015-05-12 US disclosed
US-9029457-B2 Silica-supported oligomeric hybrid materials THE UNIVERSITY OF KANSAS (US) 2015-05-12 US disclosed
US-9029457-B2 Silica-supported oligomeric hybrid materials THE UNIVERSITY OF KANSAS (US) 2015-05-12 US disclosed
CN-1291971-C Flavourant compounds GIVAUDAN SA (CH) 2006-12-27 CN disclosed
US-20050233042-A1 Flavourant compounds GIVAUDAN SA (CH) 2005-10-20 US disclosed
CN-1668578-A Flavourant compounds GIVAUDAN SA (CH) 2005-09-14 CN disclosed
EP-1525184-A1 FLAVOURANT COMPOUNDS Givaudan SA (CH) 2005-04-27 EP disclosed
WO-2004011415-A1 FLAVOURANT COMPOUNDS GIVAUDAN SA (CH) 2004-02-05 WO disclosed