Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572806 | 0.85 | PDE4A (0.58) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7425104 | 0.81 | PDE4A (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6233343 | 0.80 | PDE4A (0.63) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6229209 | 0.79 | PDE4B (0.50) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6230325 | 0.79 | PDE4A (0.49) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8925164 | 0.78 | PDE4A (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7357352 | 0.78 | PDE4B (0.53) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6889943 | 0.76 | PDE4A (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL9283831 | 0.76 | PDE4B (0.53) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL4822025 | 0.75 | PDE4A (0.79) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933366-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6235739-B1 | ANTIINFLAMMATORY AGENTS; ANTIHISTAMINES; SKIN DISORDERS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0933366-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-08-04 | — | — | EP | disclosed |