SCHEMBL6231906

SCHEMBL6231906

C=CCc1c(C(C)C)ccc(C)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRB2 P47870 3/20 0.35
PTGS1 P23219 3/20 0.35
LMNA P02545 2/20 0.35
SLC6A2 P23975 2/20 0.35
HTR2B P41595 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
FAAH O00519 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
HTR2C P28335 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6229370 0.86 PTGS1 (0.39) GABRA1GABRG2GABRB3GABRB2PTGS1
SCHEMBL8630736 0.84 GABRA1 (0.35) GABRA1GABRG2GABRB3LMNASLC6A2
SCHEMBL8316943 0.81 GABRA1 (0.39) GABRA1GABRB2PTGS1CYP3A4HPGD
SCHEMBL6321869 0.78 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2PTGS1
SCHEMBL8850895 0.77 GABRA1 (0.42) GABRA1GABRB2PTGS1LMNASLC6A2
SCHEMBL5849196 0.77 GABRA1 (0.44) GABRA1GABRB2PTGS1GAAKDM4E
SCHEMBL9028182 0.76 GABRA1 (0.33) GABRA1GABRG2GABRB3GABRB2PTGS1
SCHEMBL15914234 0.75 GABRA1 (0.47) GABRA1GABRG2GABRB3GABRB2PTGS1
SCHEMBL30474389 0.75 GAA (0.35) GABRA1GABRB2PTGS1HPGDGAA
SCHEMBL6229368 0.75 GABRA1 (0.38) GABRA1GABRG2GABRB3GABRB2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053744-B1 Substituted phenols as fragrance, flavor and antimicrobial compounds TAKASAGO PERFUMERY CO LTD (JP) 2005-04-27 EP claimed
EP-1053744-A2 Substituted phenols as fragrance, flavor and antimicrobial compounds Takasago International Corporation (JP) 2000-11-22 EP claimed
US-6110888-A PHENOL SUBSTITUTED WITH ONE OF: PROPYL OR PROPENYL; ONE OF: HYDROGEN OR ALKYL; AND ONE TO THREE C3-C5 ALKYL GROUPS; FRAGRANCE AND ANTIMICROBIAL PROPERTIES; USE SUCH AS IN MOUTHWASHES TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-08-29 US claimed
EP-1053744-B1 Substituted phenols as fragrance, flavor and antimicrobial compounds TAKASAGO PERFUMERY CO LTD (JP) 2005-04-27 EP disclosed
EP-1053744-A2 Substituted phenols as fragrance, flavor and antimicrobial compounds Takasago International Corporation (JP) 2000-11-22 EP disclosed
US-6110888-A PHENOL SUBSTITUTED WITH ONE OF: PROPYL OR PROPENYL; ONE OF: HYDROGEN OR ALKYL; AND ONE TO THREE C3-C5 ALKYL GROUPS; FRAGRANCE AND ANTIMICROBIAL PROPERTIES; USE SUCH AS IN MOUTHWASHES TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-08-29 US disclosed