Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.68 |
| ▸ | MPO | P05164 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15663052 | 0.98 | TAAR1 (0.71) | TAAR1MPOSLC6A4AOC3MAOA | |
| SCHEMBL1287446 | 0.91 | TAAR1 (0.74) | TAAR1MPOSLC6A4AOC3MAOA | |
| SCHEMBL26077417 | 0.86 | MAOA (0.58) | TAAR1MPOSLC6A4MAOAHRH1 | |
| SCHEMBL30660239 | 0.84 | TAAR1 (0.68) | TAAR1MPOSLC6A4AOC3IDO1 | |
| SCHEMBL3680377 | 0.84 | MAOA (0.61) | TAAR1MPOSLC6A4MAOAHRH1 | |
| SCHEMBL28243792 | 0.82 | TAAR1 (0.67) | TAAR1MPOSLC6A4AOC3IDO1 | |
| SCHEMBL158935 | 0.81 | TAAR1 (1.00) | TAAR1MPOSLC6A4AOC3IDO1 | |
| SCHEMBL29401035 | 0.81 | TAAR1 (1.00) | TAAR1MPOSLC6A4AOC3IDO1 | |
| SCHEMBL863377 | 0.81 | TAAR1 (0.54) | TAAR1MPOSLC6A4AOC3IDO1 | |
| SCHEMBL19391589 | 0.81 | TAAR1 (0.54) | TAAR1MPOSLC6A4AOC3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |