Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252632 | 0.89 | NPC1 (0.48) | PTPN1ALOX5NPC1HPGDMAPK1 | |
| SCHEMBL5587159 | 0.74 | PTPN1 (0.50) | PGAM1PTPN1ALOX5CA1CA2 | |
| SCHEMBL18371594 | 0.74 | HPGD (0.39) | PGAM1PTPN1NPC1HPGDMAPK1 | |
| SCHEMBL6232640 | 0.73 | CNR1 (0.39) | PGAM1HPGDCNR1CNR2ALOX15 | |
| SCHEMBL28871536 | 0.73 | CNR1 (0.39) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL19729139 | 0.73 | PTPN1 (0.38) | PGAM1PTPN1ALOX5CA1CA2 | |
| SCHEMBL6232082 | 0.73 | TSHR (0.36) | ALOX5HTT | |
| SCHEMBL5678564 | 0.72 | HTT (0.47) | PTPN1ALOX5CA1CA2CA4 | |
| SCHEMBL5589047 | 0.71 | HMGCR (0.42) | PGAM1PTPN1ALOX5NPC1HPGD | |
| SCHEMBL5678265 | 0.71 | ALOX5 (0.43) | PGAM1ALOX5NPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |