Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262048 | 1.00 | GAA (0.67) | GAALMNAHTR6C5AR1ALDH1A1 | |
| SCHEMBL6228574 | 0.83 | GAA (0.46) | GAALMNAHTR6ALDH1A1HTT | |
| SCHEMBL6228572 | 0.83 | GAA (0.46) | GAALMNAHTR6ALDH1A1HTT | |
| SCHEMBL15761364 | 0.81 | GAA (1.00) | GAALMNAC5AR1ALDH1A1POLB | |
| SCHEMBL29751607 | 0.81 | GAA (1.00) | GAALMNAC5AR1ALDH1A1POLB | |
| SCHEMBL489379 | 0.79 | LMNA (0.58) | GAALMNAC5AR1ALDH1A1POLB | |
| SCHEMBL31000980 | 0.79 | GAA (0.68) | GAAHTR6C5AR1ALDH1A1CA12 | |
| SCHEMBL11853033 | 0.79 | GAA (0.68) | GAAHTR6C5AR1ALDH1A1CA12 | |
| SCHEMBL6229583 | 0.76 | LMNA (0.54) | GAALMNAC5AR1ALDH1A1POLB | |
| SCHEMBL6229585 | 0.76 | LMNA (0.54) | GAALMNAC5AR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076651-B1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6573288-B1 | Compounds are inhibitors of the sodium-dependent bicarbonate/chloride ion exchanger which can be used as medicines for the prophylaxis or treatment of a wide range of diseases, for example the treatment and/or prophylaxis of | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-06-03 | — | — | US | disclosed |
| EP-1076651-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999057102-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-11 | — | — | WO | disclosed |