Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125593 | 0.84 | PPARA (0.61) | PPARGPPARAPTPN1PPARD | |
| SCHEMBL29358494 | 0.84 | PPARA (0.61) | PPARGPPARAPTPN1PPARD | |
| SCHEMBL3922 | 0.84 | PPARA (0.61) | PPARGPPARAPTPN1PPARD | |
| SCHEMBL4055559 | 0.84 | PPARG (0.54) | PPARGPPARAPTPN1FFAR1CA2 | |
| SCHEMBL14379043 | 0.84 | PPARA (0.61) | PPARGPPARAPTPN1PPARD | |
| SCHEMBL8981746 | 0.80 | PPARA (0.54) | PPARGPPARAPTPN1FFAR1PPARD | |
| SCHEMBL8981743 | 0.80 | PPARA (0.54) | PPARGPPARAPTPN1FFAR1PPARD | |
| SCHEMBL5707014 | 0.79 | PTPN1 (0.64) | PPARGPPARAPTPN1FFAR1CA2 | |
| SCHEMBL6498084 | 0.79 | FFAR1 (0.56) | PPARGPPARAPTPN1FFAR1CA2 | |
| SCHEMBL6497355 | 0.78 | PPARG (0.54) | PPARGPPARAPTPN1FFAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213287-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | claimed |
| US-6730687-B1 | THERAPY OF METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA AS AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | claimed |
| EP-1213287-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | claimed |
| EP-1213287-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-6730687-B1 | THERAPY OF METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA AS AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1213287-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |