Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.61 |
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | PPARD | Q03181 | 6/20 | 0.59 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922 | 1.00 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL29358494 | 1.00 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL14379043 | 1.00 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL896413 | 0.93 | PPARG (0.52) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6239522 | 0.91 | PPARA (0.59) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7465714 | 0.91 | PPARG (0.50) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7462895 | 0.90 | PPARA (0.52) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL13524845 | 0.89 | PTPN1 (0.55) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL6376424 | 0.89 | POLB (0.54) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL13847876 | 0.88 | PTPN1 (0.54) | PPARAPPARGPPARDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200253937-A1 | 5-DEUTERO-THIAZOLIDINE-2,4-DIONE COMPOUNDS AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | POXEL SA (FR) | 2020-08-13 | — | — | US | disclosed |
| US-20180125827-A1 | 5-DEUTERO-THIAZOLIDINE-2,4-DIONE COMPOUNDS AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | DEUTERX, LLC | 2018-05-10 | — | — | US | disclosed |
| US-20180125827-A1 | 5-DEUTERO-THIAZOLIDINE-2,4-DIONE COMPOUNDS AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | DEUTERX, LLC | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125827-A1 | 5-DEUTERO-THIAZOLIDINE-2,4-DIONE COMPOUNDS AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | DPP4, SLC5A2, GLP1R | PPARA 26/4885PPARG 12/4885PPARD 10/4885 |
| US-20200253937-A1 | 5-DEUTERO-THIAZOLIDINE-2,4-DIONE COMPOUNDS AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | SLC5A2, GLI2, SLC5A1 | PPARA 66/4885PPARG 13/4885PPARD 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.