Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232401 | 0.88 | GLA (0.39) | MAPTHSD17B10KDM4ELMNAL3MBTL1 | |
| SCHEMBL6258847 | 0.82 | KMT2A (0.36) | MAPTHSD17B10KDM4ETP53KMT2A | |
| SCHEMBL6253644 | 0.81 | GAA (0.33) | TP53LMNAL3MBTL1GAAMAPK1 | |
| SCHEMBL5588577 | 0.80 | HSD17B10 (0.40) | MAPTHSD17B10KDM4ECA9CNR1 | |
| SCHEMBL6232608 | 0.80 | ESR1 (0.39) | MAPTHSD17B10KDM4ETP53KMT2A | |
| SCHEMBL6233314 | 0.80 | MAPT (0.41) | MAPTHSD17B10KDM4ECA9LMNA | |
| SCHEMBL5590050 | 0.78 | PTGS1 (0.40) | TP53LMNA | |
| SCHEMBL6232138 | 0.78 | CYP1A2 (0.49) | MAPTHSD17B10KMT2ALMNAMEN1 | |
| SCHEMBL27199180 | 0.76 | PTGDR2 (0.39) | ALDH1A1GAA | |
| SCHEMBL5590279 | 0.76 | MAPT (0.36) | MAPTHSD17B10KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |