Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232616 | 0.88 | MAPT (0.38) | L3MBTL1HSD17B10MAPK1LMNAKDM4E | |
| SCHEMBL6233314 | 0.82 | MAPT (0.41) | L3MBTL1TSHRHSD17B10RAB9AMAPK1 | |
| SCHEMBL8042700 | 0.81 | MAPT (0.45) | GLAL3MBTL1TSHRHSD17B10LMNA | |
| SCHEMBL6252173 | 0.81 | TSHR (0.42) | GLATSHRHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL5588498 | 0.79 | KDM4E (0.44) | GLAL3MBTL1TSHRHSD17B10NPC1 | |
| SCHEMBL27199180 | 0.79 | PTGDR2 (0.39) | CYP2C19ALDH1A1 | |
| SCHEMBL6232397 | 0.78 | ESR1 (0.43) | HSD17B10NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL6234126 | 0.78 | PTGDR2 (0.38) | L3MBTL1TSHRHSD17B10LMNAHDAC1 | |
| SCHEMBL6232095 | 0.78 | LMNA (0.33) | RAB9AMAPK1LMNAMAPTPOLB | |
| SCHEMBL6230446 | 0.78 | CYP2C19 (0.38) | TSHRHSD17B10NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |