Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233680 | 0.91 | ESR1 (0.47) | ESR1TSHRSMN1; SMN2LMNANR1H2 | |
| SCHEMBL27701586 | 0.84 | ESR1 (0.52) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6232750 | 0.82 | ESR1 (0.60) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6235654 | 0.82 | ESR1 (0.61) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL11225216 | 0.81 | TSHR (0.59) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL19636606 | 0.81 | ALDH1A1 (0.50) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6234838 | 0.81 | ESR1 (0.51) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6253047 | 0.81 | ESR1 (0.60) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6230637 | 0.79 | ESR1 (0.50) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6230570 | 0.79 | ESR1 (0.50) | ESR1TSHRSMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |