⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030843 | 1.00 | — | — | |
| SCHEMBL1033082 | 1.00 | — | — | |
| SCHEMBL1028572 | 0.72 | — | — | |
| SCHEMBL1028075 | 0.72 | — | — | |
| SCHEMBL6663608 | 0.72 | — | — | |
| SCHEMBL19508366 | 0.72 | — | — | |
| Isobutyraldehyde SCHEMBL2635854 | 0.70 | ADH1B (0.38) | — | |
| SCHEMBL74788 | 0.70 | — | — | |
| Isobutyraldehyde SCHEMBL2996 | 0.70 | — | — | |
| Isobutyraldehyde SCHEMBL788159 | 0.70 | ADH1B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829516-B2 | Peptidomimetics for imaging the ghrelin receptor | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2020-11-10 | — | — | US | claimed |
| EP-3033343-B1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK | NOVARTIS AG (CH) | 2018-12-05 | — | — | EP | claimed |
| EP-2763987-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE AS FUNGICIDALS | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | claimed |
| US-20170183348-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2017-06-29 | — | — | US | claimed |
| EP-2763993-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | claimed |
| EP-3033343-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK | Novartis AG (CH) | 2016-06-22 | — | — | EP | claimed |
| US-20160136150-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK | NOVARTIS AG (CH) | 2016-05-19 | — | — | US | claimed |
| WO-2016016446-A1 | PROCESS FOR PREPARING 2-FLUOROPROPIONALDEHYDE | SANDOZ AG (CH) | 2016-02-04 | — | — | WO | claimed |
| US-9227969-B2 | Compounds and compositions as inhibitors of MEK | NOVARTIS AG (CH) | 2016-01-05 | — | — | US | claimed |
| US-9023844-B2 | Heterocyclylpyri (mi) dinylpyrazole as fungicidals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| EP-2763987-A1 | HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS | Bayer Intellectual Property GmbH (DE) | 2014-08-13 | — | — | EP | claimed |
| EP-2763993-A1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE | Bayer Intellectual Property GmbH (DE) | 2014-08-13 | — | — | EP | claimed |
| CN-102482287-B | 3-heteroarylmethyl-imidazo [1,2-B ] pyridazin-6-yl derivatives as modulators of C-Met tyrosine kinase | NOVARTIS AG | 2014-07-23 | — | — | CN | claimed |
| US-8710098-B2 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Chinese Academy of Medical Science (CN) | 2014-04-29 | — | — | US | claimed |
| CN-101535276-B | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC | 2013-08-28 | — | — | CN | claimed |
| WO-2013050434-A1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-11 | — | — | WO | claimed |
| WO-2013050437-A1 | HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-11 | — | — | WO | claimed |
| US-8119609-B2 | Apoptosis and increased production of ceramides and DAG are normalized in the presence of antioxidants | MERCK SANTE (FR) | 2012-02-21 | — | — | US | claimed |
| US-20030216290-A1 | Methods and compositions of treating and/or preventing diabetic retinopathy with pericyte apoptosis inhibitors | MERCK SANTE, A CORPORATION OF FRANCE (FR) | 2003-11-20 | — | — | US | claimed |
| US-5462705-A | Method of forming diffusely reflecting sintered fluorinated long-chain addition polymers doped with pigments for color standard use | LABSPHERE, INC. (US) | 1995-10-31 | — | — | US | claimed |