Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963199 | 0.87 | MAPT (0.47) | CDC25BMAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL11659290 | 0.80 | CYP1A2 (0.42) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL6235702 | 0.79 | ALDH1A1 (0.50) | CDC25BMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3151189 | 0.78 | MAPT (0.51) | MAPTALDH1A1ECE1KMT2AMEN1 | |
| SCHEMBL6230806 | 0.77 | MEN1 (0.43) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL6235442 | 0.75 | CDC25B (0.48) | CDC25BMAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL6233980 | 0.75 | SELL (0.45) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL3815597 | 0.74 | CSNK2A1 (0.38) | MAPTTDP1KMT2AMEN1POLB | |
| SCHEMBL13114314 | 0.73 | TSHR (0.47) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4469856 | 0.72 | CDC25B (0.78) | CDC25BMAPTTDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945450-B1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO (JP) | 2005-05-11 | — | — | EP | disclosed |
| US-6069166-A | INHIBITORY ACTIVITY AGAINST INFILTRATION OF EOSIONOPHILS, AND ARE USEFUL AS DRUGS FOR TREATING NASAL BLOCKAGE | SHIONOGI & CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0945450-A1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |