SCHEMBL6233090

SCHEMBL6233090

CC(C)c1cc([S+]([O-])c2cc(C(C)C)c(O)c(C(C)C)c2)cc(C(C)C)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
GABRA1 P14867 6/20 0.52
GABRB1 P18505 5/20 0.52
GABRB2 P47870 3/20 0.52
CYP1A2 P05177 3/20 0.44
CYP3A4 P08684 3/20 0.44
FAAH O00519 1/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRG2 P18507 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
HTR2B P41595 1/20 0.44
GABRA2 P47869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9297249 0.77 GABRA1 (0.43) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL1760529 0.72 CA1 (0.70) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL275427 0.72 CA1 (1.00) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL544651 0.70 CA1 (0.67) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL94533 0.70 GABRA1 (0.77) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL1163939 0.69 GABRA1 (1.00) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL6868812 0.69 CA1 (0.64) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL647950 0.69 CA1 (0.64) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL10966386 0.69 CA1 (0.64) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL3640323 0.69 GABRA1 (1.00) CA1CA2GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1215103-C Process for the preparation of polycarbonates DOW GLOBAL TECHNOLOGIES CO (US) 2005-08-17 CN disclosed
EP-1274762-B1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-05-11 EP disclosed
CN-1420901-A Polycarbonate preparation process DOW GLOBAL TECHNOLOGIES CO (US) 2003-05-28 CN disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US disclosed
EP-0941268-A1 POLYCARBONATES THE DOW CHEMICAL COMPANY (US) 1999-09-15 EP disclosed
WO-1998022522-A1 POLYCARBONATES THE DOW CHEMICAL COMPANY (US) 1998-05-28 WO disclosed
US-RE35499-E MOLDED ARTICLES SUCH AS COMPACT DISKS THE DOW CHEMICAL COMPANY (US) 1997-04-29 US disclosed
EP-0699702-A2 Reaction products of carbonyl compounds and dihydric phenols THE DOW CHEMICAL COMPANY (US) 1996-03-06 EP disclosed
US-4210741-A Phenolphthalein-dihydroxy aromatic compound polycarbonates THE DOW CHEMICAL COMPANY (US) 1980-07-01 US disclosed
US-4195156-A ALKALI METAL SALTS OF DIHYDROXY- BENZENE MONO OR DI SULFONIC ACIDS AS COMONOMERS THE DOW CHEMICAL COMPANY (US) 1980-03-25 US disclosed
US-4168368-A STRESS RESISTANCE THE DOW CHEMICAL COMPANY (US) 1979-09-18 US disclosed
US-4156769-A Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1979-05-29 US disclosed
US-4111910-A POLYCARBONATES HAVING CARBAMATE TERMINAL GROUPS THE DOW CHEMICAL COMPANY (US) 1978-09-05 US disclosed
US-4100139-A Polycarbonates incorporating epihalohydrin residues THE DOW CHEMICAL COMPANY (US) 1978-07-11 US disclosed
US-4059566-A Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4055544-A Process for making polycarbonates using ammonia or ammonia compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1977-10-25 US disclosed
US-4020045-A METALLIC SULFITES THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3992357-A THERMOPLASTIC THE DOW CHEMICAL COMPANY (US) 1976-11-16 US disclosed