SCHEMBL6233137

SCHEMBL6233137

CCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2-c2ccc(CC(C)CC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.59
RARB P10826 7/20 0.59
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
PLA2G4B P0C869 7/20 0.55
PLA2G4A P47712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773978 1.00 PTPN11 (0.59) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL10435819 1.00 PTPN11 (0.59) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL10435818 0.95 RARB (0.61) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL8839087 0.95 RARB (0.61) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL6233140 0.95 PTPN11 (0.64) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL10719739 0.92 PTPN11 (0.56) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL8533891 0.89 RARB (0.62) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL5065174 0.88 RARB (0.65) PTPN11RARB
SCHEMBL5355718 0.88 RARB (0.76) PTPN11RARBTP53TSHRPLA2G4B
SCHEMBL9182244 0.88 RARB (0.76) PTPN11RARBTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0840145-B1 POLARIZATION CONVERTER, OPTICAL CONVERTER, ELECTRONIC APPARATUS AND PROCESS FOR PRODUCING POLARIZATION CONVERTER SEIKO EPSON CORP (JP) 2005-04-27 EP disclosed
US-6624859-B1 Apparatus comprising optically active material which exhibits anisotropy with respect to optical activity, and increases intensity of luminous flux having particular plane of polarization and reduces that having perpendicular plane SEIKO EPSON CORPORATION (JP) 2003-09-23 US disclosed
US-5726460-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1998-03-10 US disclosed
US-5724114-A Liquid crystal device with composition containing optically active material and material showing smectic, smectic A and chiral smectic C phases upon temperature decrease CANON KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
US-5671033-A Liquid crystal device having mixture of cholesteric and smectic liquid crystals and alignment treatment on only one substrate CANON KABUSHIKI KAISHA (JP) 1997-09-23 US disclosed
US-5648830-A Liquid crystal device having composition of at least two smectic compounds and one cholesteric compound CANON KABUSHIKI KAISHA (JP) 1997-07-15 US disclosed
US-5604614-A Liquid crystal device with one liquid crystal showing a cholesteric phase and one showing a chiral smectic phase CANON KABUSHIKI KAISHA (JP) 1997-02-18 US disclosed
US-5592315-A Liquid crystal device and liquid crystal apparatus CANON KABUSHIKI KAISHA (JP) 1997-01-07 US disclosed
US-5311343-A Liquid crystal device with at least two liquid crystal compounds, one having and one not having a chiral smectic phase CANON KABUSHIKI KAISHA (JP) 1994-05-10 US disclosed
US-5301049-A Liquid crystal device with at least two liquid crystal compounds, one having one not having a cholesteric phase CANON KABUSHIKI KAISHA (JP) 1994-04-05 US disclosed
EP-0322703-A2 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1989-07-05 EP disclosed