Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 15/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499910 | 0.84 | EGFR (0.44) | NTRK1EGFRABCG2FLT1TSHR | |
| SCHEMBL6233379 | 0.82 | EGFR (0.55) | NTRK1EGFRERBB2ERBB4 | |
| SCHEMBL6233381 | 0.82 | EGFR (0.55) | NTRK1EGFRERBB2ERBB4 | |
| SCHEMBL6236027 | 0.71 | EGFR (0.47) | NTRK1EGFRERBB2FLT1 | |
| SCHEMBL6252739 | 0.70 | EGFR (0.42) | NTRK1EGFRERBB2ERBB4 | |
| SCHEMBL6239430 | 0.69 | EGFR (0.55) | EGFRERBB2ERBB4 | |
| SCHEMBL6238635 | 0.69 | EGFR (0.71) | EGFRERBB2ERBB4 | |
| SCHEMBL6239860 | 0.68 | EGFR (0.58) | EGFRERBB2ERBB4 | |
| SCHEMBL6235814 | 0.68 | EGFR (0.49) | EGFRKDRTSHRHTT | |
| SCHEMBL6240056 | 0.68 | EGFR (0.54) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |