SCHEMBL7945104

SCHEMBL7945104

CCOC(=O)C(=Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1)C(=O)OCC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.66
KMT2A Q03164 8/20 0.66
MAPT P10636 8/20 0.65
LMNA P02545 3/20 0.65
NPSR1 Q6W5P4 3/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
S1PR4 O95977 1/20 0.65
S1PR1 P21453 1/20 0.65
MAPK1 P28482 1/20 0.65
NR1H4 Q96RI1 1/20 0.53
DHODH Q02127 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 4/20 0.51
HSP90AA1 P07900 2/20 0.51
HTT P42858 2/20 0.51
MITF O75030 1/20 0.51
POLB P06746 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19049494 1.00 MEN1 (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL21183312 0.95 MEN1 (0.72) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL19038366 0.94 KMT2A (0.59) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL15095092 0.92 MEN1 (0.77) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL1068265 0.87 MEN1 (0.85) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL6233430 0.86 KMT2A (0.68) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL11484470 0.84 MEN1 (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL11824063 0.84 MEN1 (0.70) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL11824071 0.84 MEN1 (0.70) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10890387 0.84 KMT2A (0.65) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6168911-B1 A POLYESTERIONOMER CONTAINING A REPEATING UNITS OF THE CONDENSATION RESIDUES OF A FIRST DICARBOXYLIC ACID, A SECOND DICARBOXYLIC ACID CONTAINING AN ARYLAMINE ELECTRON DONATING GROUP AND A DIOL WITH ARYLAMINE GROUP EASTMAN KODAK COMPANY 2001-01-02 US disclosed
EP-1011019-A1 Imaging elements comprising transparent electrically conductive layers EASTMAN KODAK COMPANY (US) 2000-06-21 EP disclosed
EP-0063528-B1 CONDENSATION POLYMERIC PHOTOCONDUCTORS CONTAINING PENDANT ARYLAMINES, PHOTOCONDUCTIVE COMPOSITIONS AND ELECTROPHOTOGRAPHIC ELEMENTS CONTAINING THESE PHOTOCONDUCTORS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-19 EP disclosed
US-4463078-A POLYESTER COATINGS AND FILMS; ELECTROGRAPHY; XEROGRAPHY; LIGHT SEN EASTMAN KODAK COMPANY (US) 1984-07-31 US disclosed
US-4395475-A Condensation polymeric photoconductors containing pendant arylamines EASTMAN KODAK COMPANY (US) 1983-07-26 US disclosed
EP-0063528-A2 Condensation polymeric photoconductors containing pendant arylamines, photoconductive compositions and electrophotographic elements containing these photoconductors EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-10-27 EP disclosed