Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TERT | O14746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HK1 | P19367 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6229670 | 0.99 | CYP3A4 (0.60) | CYP3A4NFKB1HSD17B10CHRM2KMT2A | |
| Iodide SCHEMBL6233154 | 0.88 | TERT (0.62) | CYP3A4NFKB1HSD17B10CHRM2KMT2A | |
| Iodide SCHEMBL6234377 | 0.87 | TERT (0.64) | CYP3A4NFKB1HSD17B10CHRM2KMT2A | |
| SCHEMBL8071104 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL1105114 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL6263953 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL18379137 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL418871 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL18376159 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 | |
| SCHEMBL284967 | 0.85 | STAT3 (0.65) | KMT2ATERTMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027879-B1 | Use of cationic condensed polycyclic compounds for dyeing of keratinic substances, dyeing compositions and process | OREAL (FR) | 2005-04-20 | — | — | EP | claimed |