Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032272 | 0.88 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHPGDHRH4EHMT2 | |
| SCHEMBL6818739 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EHPGDHRH4EHMT2 | |
| SCHEMBL6237774 | 0.83 | EHMT2 (0.45) | ALDH1A1KDM4EHPGDTSHRCASP1 | |
| SCHEMBL5438494 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EHPGDBCL6 | |
| SCHEMBL6856412 | 0.79 | SPIN1 (0.40) | ALDH1A1KDM4EHPGDTSHREHMT2 | |
| SCHEMBL5424915 | 0.78 | EHMT2 (0.39) | EHMT2HTR2AEHMT1GALR2GALR1 | |
| SCHEMBL6920807 | 0.78 | HTT (0.42) | ALDH1A1KDM4EHPGDTSHRHRH4 | |
| SCHEMBL5421592 | 0.77 | EHMT2 (0.39) | HRH4EHMT2HTR1ADRD2HTR2A | |
| SCHEMBL4839029 | 0.77 | GALR1 (0.46) | EHMT2BCL6EHMT1FGFR3GALR2 | |
| SCHEMBL4841050 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ETSHRBCL6GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |