Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.40 |
| ▸ | KMT5A | Q9NQR1 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818739 | 0.83 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL5032272 | 0.81 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL6233712 | 0.79 | ALDH1A1 (0.39) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6237774 | 0.78 | EHMT2 (0.45) | SPIN1KMT5AHTR1ADRD2HTR2A | |
| SCHEMBL4841050 | 0.78 | SMN1; SMN2 (0.39) | LMNAPOLBTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL5438494 | 0.77 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL6863012 | 0.73 | SLC6A2 (0.34) | SPIN1KMT5ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5424915 | 0.72 | EHMT2 (0.39) | KMT5AHTR2AEHMT2GALR1 | |
| SCHEMBL4832691 | 0.71 | GALR1 (0.49) | NPSR1SMN1; SMN2HPGDKDM1AEHMT2 | |
| SCHEMBL6916172 | 0.71 | LMNA (0.43) | LMNAPOLBALOX15TSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077648-A1 | Methods and compositions of novel triazine compounds | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-04-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077648-A1 | Methods and compositions of novel triazine compounds | AREG, TGFB1, PTGIS | SPIN1 4353/4885KMT5A 2890/4885HTR1A 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.