Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 4/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15200383 | 0.80 | ALDH1A1 (0.38) | HPGDKDM4ELMNAALDH1A1HTR1B | |
| SCHEMBL2947384 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL15658735 | 0.80 | ALDH1A1 (0.48) | HPGDALDH1A1CDC25BCYP2A6TSHR | |
| SCHEMBL30356629 | 0.79 | HPGD (0.40) | HPGDKDM4ELMNAALDH1A1HTR1B | |
| SCHEMBL30356627 | 0.79 | HPGD (0.40) | HPGDKDM4ELMNAALDH1A1HTR1B | |
| SCHEMBL29390280 | 0.78 | ALDH1A1 (0.50) | HPGDALDH1A1CDC25BCYP2A6TSHR | |
| SCHEMBL135987 | 0.78 | ALDH1A1 (0.50) | HPGDALDH1A1CDC25BCYP2A6TSHR | |
| SCHEMBL11861469 | 0.75 | ALDH1A1 (0.48) | HPGDALDH1A1CDC25BCYP2A6TSHR | |
| SCHEMBL11826715 | 0.75 | ALDH1A1 (0.48) | HPGDALDH1A1CDC25BCYP2A6TSHR | |
| SCHEMBL13979769 | 0.75 | DRD1 (0.41) | HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318155-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-6624320-B2 | Phosphorane compound hydrogenation catalyts; stereospecific; catalyst selectivity | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-09-23 | — | — | US | disclosed |
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1318155-A1 | Novel asymmetric phosphine ligand | Takasago International Corporation (JP) | 2003-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | PHOSPHO1, PLCG2, PLCB3 | HPGD 4072/4885KDM4E 2892/4885LMNA 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.