Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | BCL6 | P41182 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919068 | 0.81 | BCL6 (0.41) | SMN1; SMN2PDE4ABCL6ALDH1A1MAPT | |
| SCHEMBL4829776 | 0.78 | BCL6 (0.59) | SMN1; SMN2BCL6MAPTLMNAKMT2A | |
| SCHEMBL4837927 | 0.76 | BCL6 (0.55) | SMN1; SMN2BCL6ALDH1A1MAPTKDM4E | |
| SCHEMBL6240040 | 0.74 | EGFR (0.37) | PDE4ABCL6MAPTLRRK2ALK | |
| SCHEMBL6920807 | 0.74 | HTT (0.42) | BCL6ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL4839057 | 0.72 | PTK2 (0.38) | BCL6MAPTLMNAKMT2AJAK2 | |
| SCHEMBL5556168 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2PDE4ABCL6ALDH1A1MAPT | |
| SCHEMBL6016921 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2BCL6ALDH1A1MAPTKMT2A | |
| SCHEMBL4839209 | 0.70 | EHMT2 (0.50) | SMN1; SMN2BCL6ALDH1A1MAPTKDM4E | |
| SCHEMBL5422658 | 0.70 | EHMT2 (0.43) | SMN1; SMN2PDE4ABCL6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |