Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556168 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL4874024 | 0.75 | HRH4 (0.57) | HRH4 | |
| SCHEMBL4836469 | 0.74 | HRH4 (0.45) | SMN1; SMN2MAPK1HRH4KMT2AMEN1 | |
| SCHEMBL5553578 | 0.74 | RECQL (0.39) | SMN1; SMN2ALDH1A1HSP90AA1TAS1R3TAS1R1 | |
| SCHEMBL6919803 | 0.73 | EHMT2 (0.45) | SMN1; SMN2BCL6MAPK1HRH4 | |
| SCHEMBL4838063 | 0.72 | BCL6 (0.55) | SMN1; SMN2ALDH1A1HSP90AA1PDGFRBPDGFRA | |
| SCHEMBL5031294 | 0.72 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL6233997 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1PDGFRBPDGFRABCL6 | |
| SCHEMBL6016881 | 0.71 | MAPK1 (0.36) | SMN1; SMN2ALDH1A1L3MBTL1MAPK1HRH4 | |
| SCHEMBL4832802 | 0.71 | TNK2 (0.36) | SMN1; SMN2ALDH1A1HSP90AA1L3MBTL1BCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |