Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233979 | 1.00 | LMNA (0.35) | LMNATHRBCYP2C19 | |
| SCHEMBL3955359 | 0.76 | LMNA (0.39) | LMNATHRBCYP2C19 | |
| SCHEMBL6238979 | 0.75 | — | — | |
| SCHEMBL6237706 | 0.75 | — | — | |
| SCHEMBL1302820 | 0.73 | LMNA (0.44) | LMNATHRBCYP2C19 | |
| SCHEMBL3954238 | 0.72 | LMNA (0.36) | LMNATHRBCYP2C19 | |
| SCHEMBL4765447 | 0.72 | LMNA (0.36) | LMNATHRBCYP2C19 | |
| SCHEMBL6243368 | 0.72 | HPGD (0.33) | — | |
| SCHEMBL6241949 | 0.72 | EPHX1 (0.40) | — | |
| SCHEMBL3948771 | 0.71 | LMNA (0.33) | LMNATHRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |