Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20785588 | 1.00 | ESR1 (0.47) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL30142684 | 0.91 | TP53 (0.54) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL30343462 | 0.91 | TP53 (0.54) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL217919 | 0.91 | TP53 (0.54) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL29936168 | 0.86 | ESR1 (0.47) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL2031434 | 0.86 | ESR1 (0.47) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL735990 | 0.85 | TP53 (0.48) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL13416433 | 0.83 | ESR1 (0.47) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL3420339 | 0.83 | ESR1 (0.47) | ESR1ESR2TDP1TP53PDE10A | |
| SCHEMBL20785587 | 0.83 | TP53 (0.46) | ESR1ESR2TDP1TP53PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277936-B1 | Method of preparing polycarbonate resin | LG CHEMICAL LTD (KR) | 2013-03-13 | — | — | EP | disclosed |
| US-6916505-B2 | Mannich based adducts as water based epoxy curing agents with fast cure capabilities for green concrete application | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1454935-B1 | Mannich-based adducts as water based epoxy curing agents with fast cure capabilities for green concrete application | AIR PROD & CHEM (US) | 2005-05-18 | — | — | EP | disclosed |
| US-20040176502-A1 | Water-soluble polyamine adducts | EVONIK OPERATIONS GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1454935-A1 | Mannich-based adducts as water based epoxy curing agents with fast cure capabilities for green concrete application | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6147169-A | LOW TEMPERATURE CURING MIXTURE OF REACTIVE BASE RESIN AND A CLATHRATE COMPRISING A TETRAKISPHENOL HOSTING A CURING AGENT OR CURING CATALYST; STORAGE STABILITY, CORROSION RESISTANCE, ADHESION | KANSAI PAINT CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-4197389-A | POLYEPOXIDE-POLYETHER-POLYAMINE REACTION PRODUCT | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-08 | — | — | US | disclosed |