Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142684 | 0.93 | TP53 (0.54) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL217919 | 0.93 | TP53 (0.54) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL30343462 | 0.93 | TP53 (0.54) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL6234295 | 0.85 | ESR1 (0.47) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL20785587 | 0.85 | TP53 (0.46) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL20785588 | 0.85 | ESR1 (0.47) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL16351136 | 0.85 | TRPA1 (0.50) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL2031434 | 0.83 | ESR1 (0.47) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL29936168 | 0.83 | ESR1 (0.47) | TP53TDP1TRPA1PTGS1CACNA1C | |
| SCHEMBL17272963 | 0.83 | TDP1 (0.48) | TP53TDP1TRPA1PTGS1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138263-B2 | Flexible, low dielectric loss composition and method for preparing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-03-20 | — | — | US | disclosed |
| US-20090170993-A1 | FLEXIBLE, LOW DIELECTRIC LOSS COMPOSITION AND METHOD FOR PREPARING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |