SCHEMBL623448

SCHEMBL623448

OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.43
CA2 P00918 3/20 0.36
CA1 P00915 2/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6236860 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL9450922 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL395117 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL346173 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL6236464 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1800782 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL197222 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL6443127 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL50596 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL155023 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025131038-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF PHARMACEUTICAL ACTIVES ADS THERAPEUTICS LLC (US) 2025-06-26 WO claimed
CN-119954695-A Modifier and modified KNO3Powder, and preparation method and application thereof 国网江苏省电力有限公司超高压分公司 2025-05-09 CN claimed
CN-116554383-B Preparation method of polyvinylidene fluoride resin 万华化学集团股份有限公司 2025-04-01 CN claimed
CN-119725748-A High-fluorine lithium aluminate, preparation method and application thereof, electrolyte and application thereof, and lithium battery 昆山杜克大学 2025-03-28 CN claimed
CN-119524655-A Aluminum-based MOF mixed matrix membrane based on perfluoro alcohol modification and preparation method and application thereof 南京工业大学 2025-02-28 CN claimed
CN-119505113-A Preparation method of modified silicone oil for high-temperature-resistant lubricating oil 广州加美隆润滑油有限公司 2025-02-25 CN claimed
CN-116554383-A Preparation method of polyvinylidene fluoride resin 万华化学集团股份有限公司 2023-08-08 CN claimed
CN-114907210-A Method for efficiently synthesizing polyfluorinated ester compound under normal temperature condition 扬州大学 2022-08-16 CN claimed
CN-112679739-B Side chain amphiphilic molecular brush structure organic silicone oil and preparation method thereof 中国船舶重工集团公司第七二五研究所 2022-07-08 CN claimed
CN-108727903-B Zinc oxide-based nanoparticle ink and quantum dot light-emitting diode 苏州星烁纳米科技有限公司 2021-10-19 CN claimed
EP-2940472-A1 CANCER DIAGNOSIS METHOD USING RESPIRATORY GAS Ra, Jeong Chan (KR) 2015-11-04 EP claimed
EP-2456846-B1 LUBRICANT ADDITIVE COMPRISING CARBON NANOPARTICLES INTERNAT TECHNOLOGY CT (US) 2015-09-02 EP claimed
WO-2014104649-A1 CANCER DIAGNOSIS METHOD USING RESPIRATORY GAS 주식회사 알앤엘바이오 (KR) 2014-07-03 WO claimed
EP-2456846-A1 LUBRICANT ADDITIVE International Technology Center (US) 2012-05-30 EP claimed
US-20120122743-A1 LUBRICANT AND SYNERGISTIC ADDITIVE FORMULATION INTERNATION TECHNOLOGY CENTER (NC) 2012-05-17 US claimed
WO-2011011714-A1 LUBRICANT ADDITIVE INTERNATIONAL TECHNOLOGY CENTER (US) 2011-01-27 WO claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
WO-1999024016-A1 EMULSIONS FOR AEROSOLIZATION AND DRUG DELIVERY SONUS PHARMACEUTICALS, INC. (US) 1999-05-20 WO claimed