Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 19/20 | 0.67 |
| ▸ | EGFR | P00533 | 16/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233918 | 0.94 | ERBB2 (0.65) | ERBB2EGFRERBB4 | |
| SCHEMBL6241223 | 0.94 | ERBB2 (0.65) | ERBB2EGFRERBB4 | |
| SCHEMBL6240227 | 0.92 | ERBB2 (0.66) | ERBB2EGFRERBB4 | |
| SCHEMBL6233914 | 0.86 | ERBB2 (0.63) | ERBB2EGFRERBB4 | |
| SCHEMBL6235133 | 0.86 | ERBB2 (0.63) | ERBB2EGFRERBB4 | |
| SCHEMBL6238554 | 0.85 | EGFR (0.72) | ERBB2EGFR | |
| Trifluoroacetic Acid SCHEMBL6234612 | 0.85 | EGFR (0.65) | ERBB2EGFRERBB4 | |
| SCHEMBL6236609 | 0.84 | EGFR (0.53) | ERBB2EGFR | |
| SCHEMBL6493597 | 0.84 | ERBB2 (0.58) | ERBB2EGFR | |
| SCHEMBL6493599 | 0.84 | ERBB2 (0.58) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |