Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 18/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232961 | 0.93 | ERBB2 (0.51) | EGFRERBB2 | |
| SCHEMBL6241223 | 0.90 | ERBB2 (0.65) | EGFRERBB2 | |
| SCHEMBL6233918 | 0.90 | ERBB2 (0.65) | EGFRERBB2 | |
| SCHEMBL6234701 | 0.84 | ERBB2 (0.67) | EGFRERBB2 | |
| SCHEMBL6240170 | 0.83 | ERBB2 (0.60) | EGFRERBB2 | |
| SCHEMBL6235133 | 0.82 | ERBB2 (0.63) | EGFRERBB2 | |
| SCHEMBL6233914 | 0.82 | ERBB2 (0.63) | EGFRERBB2 | |
| SCHEMBL6236228 | 0.81 | ERBB2 (0.67) | EGFRERBB2 | |
| SCHEMBL6237280 | 0.81 | ERBB2 (0.67) | EGFRERBB2 | |
| SCHEMBL6232567 | 0.81 | ERBB2 (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |