Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234802 | 1.00 | GSK3B (0.54) | GSK3BIGF1RHPGDMGAMGAA | |
| SCHEMBL2882685 | 0.94 | GSK3B (0.60) | GSK3BIGF1RHPGDMGAMGAA | |
| SCHEMBL2882683 | 0.94 | GSK3B (0.60) | GSK3BIGF1RHPGDMGAMGAA | |
| SCHEMBL2882560 | 0.87 | GSK3B (0.68) | GSK3BIGF1RHPGDMGAMGAA | |
| SCHEMBL2882561 | 0.87 | GSK3B (0.68) | GSK3BIGF1RHPGDMGAMGAA | |
| SCHEMBL2880421 | 0.76 | PIM1 (0.55) | GSK3BIGF1RHPGDPIM1PIM2 | |
| SCHEMBL2880397 | 0.76 | PIM1 (0.55) | GSK3BIGF1RHPGDPIM1PIM2 | |
| SCHEMBL4852825 | 0.73 | GSK3B (0.81) | GSK3BIGF1RHPGDESRRAMAPT | |
| SCHEMBL4852830 | 0.73 | GSK3B (0.81) | GSK3BIGF1RHPGDESRRAMAPT | |
| SCHEMBL9831864 | 0.70 | GSK3B (1.00) | GSK3BIGF1RHPGDMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531813-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004006916-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) | 2004-01-22 | — | — | WO | disclosed |